Rolim 2015 (Conference Paper) Medicine

HPLC analysis of Bromeliaceae species with therapeutic activity for the development of herbal medicines

Author(s):—Larissa Araújo Rolim in Benko-Iseppon, A.M.; Alves, M. & Louzada, R. (2015) An overview and abstracts of the First World Congress on Bromeliaceae Evolution. Rodriguésia 66(2): A1-A66.

Publication:— (2015).

Abstract:—Some species of the Bromeliaceae family are widely distributed in the Brazilian semiarid and are used by the local population as an excellent source of hard fiber. Such uses include that by artisans of the San Francisco Valley region for the manufacture of wicker baskets, by the textile industry and by landscapers as ornamental plants. In addition, these species are quite often fed to goats, which with the predatory extraction of man, leads to the condition of endangered species. It was decided, therefore, to investigate Bromelia laciniosa,Encholirium spectabile and Neoglaziovia variegata before they become extinct without their chemical and pharmacological properties being known. Considering the large number of species of this family, few of them have been studied chemically yet. Nevertheless, there is a considerable amount of identified compounds, which mainly belong to the classes of flavonoids and triterpenoids related to various pharmacological activities. Work developed by the Universidade Federal do Vale do São Francisco showed that crude extracts of species of bromeliads have antinociceptive activity, peripheral and central analgesic activity, antimicrobial activity and sunscreen. Therefore, it is extremely important to qualitatively and quantitatively study the secondary metabolites by high performance liquid chromatography (HPLC -DAD), in order to identify possible chemical and pharmacological markers. Chemical assessment with the development of analytical methods by HPLC - DAD of some species of Bromeliaceae plants, identified and quantified the presence of bioactive substances, seeking the use of these extracts with therapeutic activity. The goal to this research is to contributescientifically to the industrial production of herbal medicines from Bromeliaceae species.

Keywords:—Analysis; HPLC; Activity.